6-Diazo-5-oxo-L-nor-Leucine

Description: 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 µM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil. Target: Antibacterial, Antibiotic, Glutaminase, Influenza Virus. Smiles: N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O. References: Willis RC, et al. The inhibition by 6-diazo-5-oxo-l-norleucine of glutamine catabolism of the cultured human lymphoblast. J Cell Physiol. 1977 Dec,93(3):375-82.