6-Carboxytetramethylrhodamine

6-Carboxytetramethylrhodamine is a fluorescent dye that has commonly been used for the covalent labeling of oligonucleotides for DNA analysis. It displays excitation/emission maxima of 543/572 nm, respectively. 6-Carboxytetramethylrhodamine has been used in various DNA-protein binding studies, DNA FRET experiments, and as a standard reporter or quencher dye in RT-PCR.Formal Name: 9-(2,5-dicarboxyphenyl)-3,6-bis(dimethylamino)-xanthylium, inner salt. CAS Number: 91809-67-5. Synonyms: 6-TAMRA. Molecular Formula: C25H22N2O5. Formula Weight: 430.5. Purity: >95%. Emission: 572 nm. Excitation: 543 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 2mg/mL, DMF:PBS (pH 7.2) (1:5): 0.16mg/mL, DMSO: 1mg/mL. lambdamax: 253, 353, 546 nm. SMILES: [O-]C(C(C=CC(C(O)=O)=C1)=C1C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)=O. InChi Code: InChI=1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31). InChi Key: COCMHKNAGZHBDZ-UHFFFAOYSA-N.