5,6-Dihydrouridine

5,6-Dihydrouridine is a pyrimidine nucleoside and derivative of uridine (Cay-20300). It is present in, and provides conformational flexibility to, tRNA from bacteria, eukaryotes, and some archaea. 5,6-Dihydrouridine inhibits E. coli cytidine deaminase in a cell-free assay (Ki = 3.4 µM). Serum levels of 5,6-dihydrouridine are increased in patients with prostate cancer and positively correlated with lethality.Formal Name: 5,6-dihydro-uridine. CAS Number: 5627-05-4. Synonyms: DHU. Molecular Formula: C9H14N2O6. Formula Weight: 246.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 16 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: O[C@H]1[C@@](N2C(NC(CC2)=O)=O)([H])O[C@@H]([C@H]1O)CO. InChi Code: InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1. InChi Key: ZPTBLXKRQACLCR-XVFCMESISA-N.