4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline

4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate. It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds. It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Cay-10483), with antiproliferative activity.CAS Number: 183322-18-1. Molecular Formula: C14H17ClN2O4. Formula Weight: 312.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml, DMSO: 10 mg/ml, Ethanol: 1 mg/ml. lambdamax: 222, 244 nm. SMILES: ClC1=NC=NC2=C1C=C(OCCOC)C(OCCOC)=C2. InChi Code: InChI=1S/C14H17ClN2O4/c1-18-3-5-20-12-7-10-11(16-9-17-14(10)15)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3. InChi Key: ZPJLDMNVDPGZIU-UHFFFAOYSA-N.