20(R)-Protopanaxatriol

20(R)-Protopanaxatriol is a degradation product of panaxatriols and an isomer of 20(S)-panaxatriol (Cay-29073). It is cytotoxic to P388, L1210, and K562 leukemia cells (EC50s = 34, 32, and 38 µM). 20(R)-Protopanaxatriol inhibits EGFR (IC50 = 24.1 µM) in a cell-free assay and is cytotoxic to HepG2 cells when used at concentrations ranging from 20 to 100 µM.Formal Name: (3beta,6alpha,12beta,20R)-dammar-24-ene-3,6,12,20-tetrol. CAS Number: 1453-93-6. Synonyms: 20(R)-APPT, 20(R)-PPT. Molecular Formula: C30H52O4. Formula Weight: 476.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])[C@@H](O)C[C@]3(C)[C@]2([H])C[C@@H](O)[C@@]4([H])[C@@]3(C)CC[C@]4([H])[C@](C)(O)CC/C=C(C)/C. InChi Code: InChI=1S/C30H52O4/c1-18(2)10-9-13-30(8,34)19-11-15-28(6)24(19)20(31)16-22-27(5)14-12-23(33)26(3,4)25(27)21(32)17-29(22,28)7/h10,19-25,31-34H,9,11-17H2,1-8H3/t19-,20+,21-,22+,23-,24-,25-,27+,28+,29+,30+/m0/s1. InChi Key: SHCBCKBYTHZQGZ-DLHMIPLTSA-N. Origin: Plant/Ginseng Radix Et Rhizoma.