2-Hydroxy Ibuprofen

Description: 2-Hydroxy Ibuprofen, a metabolite of Ibuprofen, an anti-inflammatory inhibitor targeting COX-1/COX-2 (IC50s: 13 µM/370 µM). Target: Others. Smiles: CC(C(O)=O)c1ccc(CC(C)(C)O)cc1. References: Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan,61(1):2-7.