2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)

2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay32566-25 25 mg -

6 - 10 Werktage*

94,00 €
Cay32566-50 50 mg -

6 - 10 Werktage*

166,00 €
Cay32566-100 100 mg -

6 - 10 Werktage*

313,00 €
Cay32566-250 250 mg -

6 - 10 Werktage*

642,00 €
 
2'-Deoxyadenosine-5'-O-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic... mehr
Produktinformationen "2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)"
2'-Deoxyadenosine-5'-O-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate (Cay-14498). dATP is a substrate for DNA polymerase in the synthesis of DNA. It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis. dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications. dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.Formal Name: ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate, trisodium salt, hydrate. Synonyms: dATP. Molecular Formula: C10H13N5O12P3 . 3Na [XH2O]. Formula Weight: 557.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 259 nm. SMILES: NC1=NC=NC2=C1N=CN2[C@@]3([H])C[C@H](O)[C@@H](COP(OP(OP(O)([O-])=O)([O-])=O)([O-])=O)O3.[Na+].[Na+].[Na+].O. InChi Code: InChI=1S/C10H16N5O12P3.3Na.H2O/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19,,,,/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19),,,,1H2/q,3*+1,/p-3/t5-,6+,7+,,,,/m0..../s1. InChi Key: RQGMMLFBAUODIH-YYWCTZDQSA-K.
Schlagworte: ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate, trisodium salt, hydrate
Hersteller: Cayman Chemical
Hersteller-Nr: 32566

Eigenschaften

Anwendung: Purine nucleotide, DNA polymerase substrate, noncompetitive ribonucleotide reductase inhibitor
MW: 557.1 D
Formel: C10H13N5O12P3 . 3Na [XH2O]
Reinheit: >95%
Format: Crystalline Solid

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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