2'-Deoxyadenosine-5'-O-diphosphate (sodium salt)

2'-Deoxyadenosine-5'-O-diphosphate (dADP) (sodium salt) is a purine nucleotide diphosphate. It inhibits the polymerization of ADP and CDP by E. coli or P. fluorescens polynucleotide phosphorylase when used at a concentration of 0.23 mM. dADP levels are increased in erythrocytes isolated from patients with adenosine deaminase (ADA) deficiency, an inborn error of metabolism characterized by severe combined immunodeficiency (SCID).Formal Name: 2'-deoxy-adenosine 5'-(trihydrogen diphosphate), trisodium salt. CAS Number: 402491-35-4. Synonyms: dADP, 2'-deoxy-ADP. Molecular Formula: C10H12N5O9P2 . 3Na. Formula Weight: 477.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 260 nm. SMILES: NC1=NC=NC2=C1N=CN2[C@@]3([H])C[C@H](O)[C@@H](COP(OP([O-])([O-])=O)([O-])=O)O3.[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C10H15N5O9P2.3Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19,,,/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19),,,/q,3*+1/p-3/t5-,6+,7+,,,/m0.../s1. InChi Key: OFUJHRQLQPLGNA-PWDLANNDSA-K.