10-Nitrooleic acid

Description: CXA-10 is an endogenous nitro-fatty acid (NFA) modulator of Nrf2 and NF-kappaB. CXA-10 upregulates expression of caveolin-1, the major structural component of caveolae. Target: Others. Smiles: C(=C\CCCCCCCC(O)=O)(\CCCCCCCC)/N(=O)=O. References: Zheng R, Heck DE, Black AT, Gow A, Laskin DL, Laskin JD. Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radic Biol Med. 2014 Feb,67:1-9. doi: 10.1016/j.freeradbiomed.2013.10.011. PubMed PMID: 24140437, PubMed Central PMCID: PMC4391631.