1-O-Hexadecyl-sn-glycerol

Description: 1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 µM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury. Target: Others. Smiles: C(CCCCCCCCCC CCCC)COC[C@H](CO)O. References: Yokota, M., Yahagi, S., Tokudome, Y., et al. Chimyl alcohol suppresses PGE2 synthesis by human epidermal keratinocytes through the activation of PPAR-gamma J. Oleo. Sci. 67(4), 455-462 (2018).