1-Hydroxyibuprofen

The metabolite 1-Hydroxyibuprofen (Ibuprofen Impurity L) is a degradation product of Ibuprofen which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain from various conditions such as headache, dental pain or menstrual cramps. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2. Ibuprofen is metabolized in the human liver to a number of metabolites including 1-hydroxyibuprofen (1-OH-Ibu), 2-OH-Ibu and 3-OH-Ibu, respectively. 1-Hydroxyibuprofen was determined as the dominant compound in soils. This product can be used as a working standard or secondary analytical reference standard.