1-Hydroxyanthraquinone

1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone (5 and 500 µM) increases the percentage of isolated rat hepatocytes undergoing unscheduled DNA synthesis, indicating genotoxic activity. Dietary administration of 1-hydroxyanthraquinone (1%) induces formation of cecum and colon adenocarcinomas, as well as hepatocellular carcinomas, in rats.Formal Name: 1-hydroxy-9,10-anthracenedione. CAS Number: 129-43-1. Synonyms: NSC 8640. Molecular Formula: C14H8O3. Formula Weight: 224.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 30 mg/ml. lambdamax: 217, 250 nm. SMILES: O=C1C2=C(C(C3=C1C=CC=C3O)=O)C=CC=C2. InChi Code: InChI=1S/C14H8O3/c15-11-7-3-6-10-12(11)14(17)9-5-2-1-4-8(9)13(10)16/h1-7,15H. InChi Key: BTLXPCBPYBNQNR-UHFFFAOYSA-N. Origin: Synthetic.