1-Hydroxy-ibuprofen

Description: 1-Hydroxy Ibuprofen, a metabolite of Ibuprofen in P. australis[1], functions as an anti-inflammatory inhibitor specifically targeting COX-1 and COX-2, with inhibitory concentration 50 (IC50) values of 13 µM and 370 µM, respectively[1]. Target: Others. Smiles: CC(C)C(O)c1ccc(cc1)C(C)C(O)=O. References: Yujie He, et al. Metabolism of Ibuprofen by Phragmites australis: Uptake and Phytodegradation. Environ Sci Technol. 2017 Apr 18,51(8):4576-4584.