1-Aminodecylidene bis-Phosphonic Acid

1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM). It is selective for acid sphingomyelinase over neutral sphingomyelinase (IC50 = >100 µM). 1-Aminodecylidene bis-phosphonic acid completely inhibits apoptosis induced by dexamethasone (Cay-11015) in HepG2 cells.Formal Name: (1-aminodecane-1,1-diyl)diphosphonic acid. CAS Number: 15049-93-1. Synonyms: 1-Amindecane-1,1-Diphosphonic Acid, ARC 39. Molecular Formula: C10H25NO6P2. Formula Weight: 317.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. SMILES: NC(CCCCCCCCC)(P(O)(O)=O)P(O)(O)=O. InChi Code: InChI=1S/C10H25NO6P2/c1-2-3-4-5-6-7-8-9-10(11,18(12,13)14)19(15,16)17/h2-9,11H2,1H3,(H2,12,13,14)(H2,15,16,17). InChi Key: TWYYYYAFACTHMV-UHFFFAOYSA-N.