Trovafloxacin (mesylate)

Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC50 = 3.02 µg/ml) and DNA gyrase (IC50 = 7.13 µg/ml).Formal Name: 7-[(1alpha,5alpha,6alpha)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, monomethanesulfonate. CAS Number: 147059-75-4. Synonyms: CP 99,219. Molecular Formula: C20H15F3N4O3 . CH4SO3. Formula Weight: 512.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 25 mg/ml, Water: 20 mg/ml. lambdamax: 269, 342 nm. SMILES: O=C1C(C(O)=O)=CN(C2=CC=C(F)C=C2F)C3=NC(N4C[C@H]([C@]5(N)[H])[C@H]5C4)=C(F)C=C31.CS(=O)(O)=O. InChi Code: InChI=1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24,1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30),1H3,(H,2,3,4)/t10-,11+,16+,. InChi Key: DYNZICQDCVYXFW-AHZSKCOESA-N.