Taurolidine

Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity. Taurolidine and its metabolites mimic mannose by binding to the extracellular wall of bacteria, blocking adherence to epithelial and fibroblast cells. In addition to modulating immunoregulatory systems, taurolidine induces autophagy, apoptosis, and necrosis in human cancer cells. It produces cell death in malignant mesothelioma cells by oxidative stress in concert with inhibition of Akt signaling.Formal Name: 4,4'-methylenebis(tetrahydro-1,2H,4-thiadiazine) 1,1,1',1'-tetraoxide. CAS Number: 19388-87-5. Molecular Formula: C7H16N4O4S2. Formula Weight: 284.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml. SMILES: O=S1(CCN(CN2CNS(CC2)(=O)=O)CN1)=O. InChi Code: InChI=1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2. InChi Key: AJKIRUJIDFJUKJ-UHFFFAOYSA-N.