Robenidine (hydrochloride)

Robenidine is an anticoccidial agent. It is also active against methicillin-resistant S. aureus (MRSA) and vancomycin-resistant enterococci (VRE, MICs = 6.1 and 7.4 µM, respectively). Dietary administration of robenidine reduces weight gain, decreases intestinal lesion and oocyst numbers, and increases survival in E. acervulina-, E. brunetti-, E. mivati-, E. necatrix-, or E. tenella-infected chickens. Formulations containing robenidine have been used in animal feed for the prevention of coccidiosis or control of necrotic enteritis in chickens. SMILES ClC1=CC=C(C=C1)C=NNC(NN=CC2=CC=C(C=C2)Cl)=N.Cl InChi Code InChI=1S/C15H13Cl2N5.ClH/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12,/h1-10H,(H3,18,21,22),1H InChi Key LTWIBTYLSRDGHP-UHFFFAOYSA-N