Hetacillin

Hetacillin is a prodrug form of the broad-spectrum antibiotic ampicillin (Cay-14417, Cay-35740). It is converted to ampicillin via hydrolysis. Hetacillin is active against several bacteria, including E. coli, S. typhimurium, S. flexneri, H. influenzae, and S. pneumoniae (MICs = 2.5, 1.25, 2.5, 0.5, and 0.05 µg/ml, respectively). Intramammary administration of hetacillin increases the cure rate of bacterial infections in dairy cows. Formulations containing hetacillin have been used in the treatment of bovine mastitis.Formal Name: (2S,5R,6R)-6-((R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. CAS Number: 3511-16-8. Molecular Formula: C19H23N3O4S. Formula Weight: 389.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: O=C1[C@](N2C([C@](C3=CC=CC=C3)([H])NC2(C)C)=O)([H])[C@]4([H])N1[C@H](C(C)(S4)C)C(O)=O. InChi Code: InChI=1S/C19H23N3O4S/c1-18(2)13(17(25)26)21-15(24)12(16(21)27-18)22-14(23)11(20-19(22,3)4)10-8-6-5-7-9-10/h5-9,11-13,16,20H,1-4H3,(H,25,26)/t11-,12-,13+,16-/m1/s1. InChi Key: DXVUYOAEDJXBPY-NFFDBFGFSA-N.