Blasticidin S (hydrochloride)

Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been created using total synthesis. Blasticidin S (hydrochloride) is used in research to select mammalian cells transfected with the blasticidin resistance gene bsr.Formal Name: 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-beta-D-erythro-hex-2-enopyranuronic acid, monohydrochloride. CAS Number: 3513-03-9. Molecular Formula: C17H26N8O5 . HCl. Formula Weight: 458.9. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: 10 mg/ml. lambdamax: 269 nm. SMILES: O=C(N=C(N)C=C1)N1[C@H]2C=C[C@H](NC(C[C@@H](N)CCN(C(N)=N)C)=O)C(C(O)=O)O2.Cl. InChi Code: InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29,/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29),1H/t9-,10-,13+,14?,/m0./s1. InChi Key: YQXYQOXRCNEATG-GMXSUNLVSA-N. Origin: Bacterium/Streptomyces griseochromogenes.