MART-1-Specific TCR Lentivirus (Clone DMF5)

The human MART-1-specific T Cell Receptor lentiviruses (clone DMF5) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce a human TCR (clone DMF5) that specifically recognizes antigen MART-1 (Melanoma-associated antigen recognized by T cells-1, or Melan-A), and in which the TCR alpha chain and beta chain are linked by P2A. The lentiviruses also transduce a puromycin selection gene.