Uncoated Human Hepc (Hepcidin) Superset Max DIY ELISA

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
G-AEES05040.480	480 assays (5 x 96 assays)		-		9 - 20 Werktage*		919,00 €

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Uncoated Human Hepc (Hepcidin) Superset Max DIY ELISA Protein Function: Liver-produced hormone... mehr

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Produktinformationen "Uncoated Human Hepc (Hepcidin) Superset Max DIY ELISA"

Uncoated Human Hepc (Hepcidin) Superset Max DIY ELISA Protein Function: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma (PubMed:22682227, PubMed:29237594, PubMed:32814342). Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005) , Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa (PubMed:11034317, PubMed:11113131) [The Uniprot Consortium]

Schlagworte:	HAMP, Hepcidin, Putative liver tumor regressor, Liver-expressed antimicrobial peptide 1
Hersteller:	Assay Genie
Hersteller-Nr:	AEES05040

Eigenschaften

Anwendung:	ELISA
Spezies-Reaktivität:	human
Format:	Solid Phase

Datenbank Information

KEGG ID :	K23106 \| Passende Produkte
UniProt ID :	P81172 \| Passende Produkte
Gene ID :	GeneID 57817 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H317
P-Sätze:	P261, P272, P280, P302+352, P321, P333+313, P362+364, P501