Rat Thyroglobulin, TG ELISA Kit

Sample Types: serum, plasma, tissue Homogenates Detection Range: 10 ng/mL-160 ng/mL Sensitivity: 10 ng/mL Assay Principle: quantitative Measurement: CompetitiveAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. [The UniProt Consortium]