Rat RAGE ELISA Kit

Rat RAGE ELISA Kit
+ Gratis T-Shirt
Aktion:

Sichern Sie sich ein gratis "Stronger Bands" T-Shirt zu jeder Rockland-Bestellung >300 €.

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
KOA0599 1 kit - -

1 - 9 Werktage

673,00 €
 
Natural and recombinant rat RAGE. There is no detectable cross-reactivity with other relevant... mehr
Produktinformationen "Rat RAGE ELISA Kit"
Natural and recombinant rat RAGE. There is no detectable cross-reactivity with other relevant proteins. Protein function: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF- alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. [The UniProt Consortium]
Schlagworte: Rage, Ager, Receptor for advanced glycosylation end products, Advanced glycosylation end product-specific receptor
Hersteller: Rockland Immunochemicals
Hersteller-Nr: KOA0599

Eigenschaften

Anwendung: ELISA
Wirt: Rat
Reaktivität: Rat
Immunogen: Expression system for standard: NSO, Immunogen sequence: Q24-A342
Format: Solid Phase

Datenbank Information

UniProt ID : Q63495 | Finde Alternativen
Gene ID GeneID 81722 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Rat RAGE ELISA Kit"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Hier folgen Informationen zur Produktreferenz. mehr
Zuletzt angesehen