Rat IL-12 p40 ELISA Kit

ELISA Type: Sandwich. Detection Range: 12.5-800µg/mL. Sensitivity: 7.5µg/mL. Sample Types: Serum, plasma and other biological fluids. Protein function: Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. [The UniProt Consortium]