Rat alpha-glutathione S-transferases, alpha-GST ELISA Kit

Sample Types: serum, plasma, tissue homogenates, cell lysates Detection Range: 0.156 mU/mL-10 mU/mL Sensitivity: 0.039 mU/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3, 17-dione (AD) into D4-androstene-3, 17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z, 11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid. [The UniProt Consortium]