Rab35 Activation Assay Kit

Configuration-specific monoclonal antibody that recognizes Rab35-GTP, but not Rab35-GDP. The only available Rab35 activation assay kit directly measures the level of Rab35-GTP. Providing shorter experimental time. Could be used to monitor the activation of Rab35 in cells and in tissues by immunohistochemistry. Protein function: In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. [The UniProt Consortium]