Mouse Hes1 (Transcription factor HES-1) ELISA Kit (MOFI01383)

Mouse Hes1  (Transcription factor HES-1) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Mouse Hes1  (Transcription factor HES-1) in serum, plasma & cell culture supernatant samples. The Mouse Hes1  (Transcription factor HES-1) ELISA Kit accurately measures natural Mouse Hes1  (Transcription factor HES-1) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Mouse Hes1  (Transcription factor HES-1) peptide. Protein function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. [The UniProt Consortium]