IL-33 (human) ELISA Kit

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 31.25-1000 pg/ml, Sensitivity: 12pg/ml, Cross reaction: No cross reactivity with IL-1b, IL-2, IL-1a, IL-10, IL-12p70, Gp130, IL-17A, IL-23, IFNg, TNFa, Incubation time: 3h45, Sample Types: Serum, Plasma and other body fluids, Cell culture supernatants, Buffered solutions, Sample Size: 100 µl (50µl for serum/plasma) Protein function: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528). [The UniProt Consortium]