IL-17F (human) ELISA Set

Diaclone ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition., Assay Range: 15.6-500 pg/ml, Sensitivity: 6.0 pg/ml, Cross reaction: No cross reactivity with other human cytokines, Incubation time: From sample to end 3h45, Sample Types: Serum, Plasma, Cell culture supernatant, Sample Size: 100 µl Protein function: Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. [The UniProt Consortium]