Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) ELISA Kit (HUFI07492)

Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) in serum, plasma & cell culture supernatant samples. The Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) ELISA Kit accurately measures natural Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) peptide. Protein function: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior. Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation. [The UniProt Consortium]