Human IL28A / IFN lambda 2 ELISA Kit

Human IL28A / IFN lambda 2 ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG81262.96 96 wells -

6 - 14 Werktage*

824,00 €
 
Protein function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a... mehr
Produktinformationen "Human IL28A / IFN lambda 2 ELISA Kit"
Protein function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. [The UniProt Consortium]
Schlagworte: IL28A, IFNL2, IL-28A, IFN-lambda-2, Interleukin-28A, Cytokine Zcyto20, Interferon lambda-2
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG81262

Eigenschaften

Anwendung: ELISA
Spezies-Reaktivität: human
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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