Human HO-1 - HMOX1 ELISA Kit

Natural and recombinant human HO-1. There is no detectable cross-reactivity with other relevant proteins. Protein function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. [The UniProt Consortium]