Human C4b-binding protein beta chain (C4BPB) ELISA kit

Sample Types: serum, plasma, cell culture supernates, tissue homogenates Detection Range: 3.12 ng/mL-200 ng/mL Sensitivity: 0.78 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. [The UniProt Consortium]