DNA/RNA Oxidative Damage Express ELISA Kit

Cayman Chemical DNA/RNA Oxidative Damage Express Kit detects all three oxidized guanine/guanosine species. 8-OHdG from DNA, 8-OHG from RNA, and 8-hydroxyguanine from either DNA or RNA. Some commercial vendors offer immunoassays that detect only 8-OHdG, and not the other two molecules. The advantage of the Cayman kit is that it captures a more complete set of biologically relevant products of oxidative damage than do assays that are restricted to analysis of only 8-OHdG., , However, because Cayman's kit recognizes more than 8-OHdG, it is not valid to compare the results from the Cayman ELISA Kit to an LC/MS analysis of 8-OHdG. The ELISA value will always be significantly higher than LC/MS because the ELISA also detects 8-OHG and 8-hydroxyguanine., , This express assay has a range from 34.3-10,000 pg/ml and a lower limit of detection (LLOD) of 62 pg/ml.