Arf6 Activation Assay Kit

Configuration-specific monoclonal antibody that recognizes Arf6-GTP, but not Arf6-GDP. The only available Arf6 activation assay kit directly measures the level of Arf6-GTP. Providing shorter experimental time. Could be used to monitor the activation of Arf6 in cells and in tissues by immunohistochemistry. Protein function: GTP-binding protein involved in protein trafficking, regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development. Contributes to the regulation of dendritic branching and filopodia extension. [The UniProt Consortium]