Angiopoietin-2 (human) ELISA Kit

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 4000-125 pg/ml, Sensitivity: 25 pg/ml, Cross reaction: No cross reactivity with VEGF-A, GM-CSF, IL-34, IL-29 IFNg, IL-2, IL-10, CD138, MICB, MCP-1, Incubation time: 3h45, Sample Types: Serum, Cell culture supernatant, Sample Size: 50 µl Protein function: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. [The UniProt Consortium]