Anti-Human THAP3 Antibody Pair

Product Description: THAP domain-containing protein 3 (THAP3) is a transcription factor characterized by the presence of a THAP (Thanatos-associated protein) domain, which is involved in DNA binding and gene regulation. This protein plays a significant role in various biological processes, including cell differentiation and development. THAP3 has been shown to interact with other transcription factors and co-regulators, influencing the expression of target genes crucial for cellular function. Dysregulation of THAP3 has been implicated in several diseases, altered expression of THAP3 has been associated with tumor growth and progression in various cancers, including breast and prostate cancer. The protein's ability to modulate gene expression can contribute to oncogenic pathways, promoting cell proliferation and survival. Additionally, THAP3 may be involved in neurodevelopmental disorders, as its expression is critical during neuronal differentiation. Protein Function: Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1 [The Uniprot Consortium]