Anti-Human Cathepsin H Antibody Pair

Product Description: Cathepsin H (CTSH) is a lysosomal cysteine protease that plays a crucial role in the degradation of proteins within lysosomes. It is synthesized as an inactive precursor and undergoes proteolytic activation, resulting in a mature form that exhibits both aminopeptidase and endopeptidase activities. This protein is composed of disulfide-linked heavy and light chains and is involved in various physiological processes, including protein turnover and immune responses. The enzyme's activity is optimal at neutral pH, allowing it to function effectively in both lysosomal and extracellular environments. Increased expression of CTSH has been associated with the progression of several cancers, including prostate and breast cancer, where it influences tumor cell behavior by modulating integrin activation and cell migration. Protein Function: Important for the overall degradation of proteins in lysosomes [The Uniprot Consortium]