Produkte von NSJ Bioreagents
Die Mitarbeiter von NSJ Bioreagents aus San Diego, Kalifornien sind seit über 20 Jahren Teil der Biotechnologie-Community im Bereich der Antikörperproduktion. Das Produktportfolio von NSJ Bio versorgt Naturwissenschaftler*innen zum Einen mit klassischen, weit verbreiteten monoklonalen Antikörpern und zum Anderen mit neu für den Markt entwickelten mono- und polyklonale Antikörpern. Dabei deckt das Unternehmen zahlreiche Bereiche der Forschung, einschließlich Krebs, Apoptose, Immunologie, Zellbiologie, Transkriptionsfaktoren und Epigenetik ab.
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Anti-NES / Nestin
Artikelnummer: NSJ-F47834-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression...
| Schlagworte: | Anti-NES, Anti-Nestin, NES Antibody / Nestin |
| Anwendung: | WB, IHC, IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-Cyclin D1 / CCND1
Artikelnummer: NSJ-F48111-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CCND1 is the regulatory component of the Cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the...
| Schlagworte: | Anti-CCND1, Anti-PRAD1 oncogene, Anti-BCL-1 oncogene, Anti-G1/S-specific cyclin-D1, Anti-B-cell lymphoma 1 protein, Cyclin... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-Vimentin
Artikelnummer: NSJ-F48161-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Vimentin (VIM) is a type III intermediate filament protein that forms a highly organized cytoplasmic filament network in mesenchymal cells, where it maintains structural integrity and regulates cellular morphology. Vimentin Antibody for IF / Cytoskeletal Filament Marker...
| Schlagworte: | Anti-VIM, Anti-Vimentin, Vimentin Antibody |
| Anwendung: | IF, WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-SSB / Lupus La protein
Artikelnummer: NSJ-F48218-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs...
| Schlagworte: | Anti-SSB, Anti-La autoantigen, Anti-Lupus La protein, Anti-La ribonucleoprotein, Anti-Sjoegren syndrome type B antigen,... |
| Anwendung: | IHC, FC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-SSB / Lupus La protein
Artikelnummer: NSJ-F48219-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SSB binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. [UniProt]
| Schlagworte: | Anti-SSB, Anti-La autoantigen, Anti-Lupus La protein, Anti-La ribonucleoprotein, Anti-Sjoegren syndrome type B antigen,... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-HER2 / ErbB2 (pY1248)
Artikelnummer: NSJ-F48395-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ErbB2 receptor tyrosine kinase 2 (ERBB2), also known as HER2, is a transmembrane receptor that plays a central role in regulating cell proliferation, survival, and differentiation through activation of intracellular signaling pathways. Phospho-ErbB2 (pY1248) antibody, also...
| Schlagworte: | Anti-ERBB2, Anti-p185erbB2, Anti-Proto-oncogene Neu, Anti-Proto-oncogene c-ErbB-2, Anti-Metastatic lymph node gene 19... |
| Anwendung: | WB, DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-p21 / CDKN1A (pT57)
Artikelnummer: NSJ-F48425-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by...
| Schlagworte: | Anti-p21, Anti-CDKN1A, Anti-CDK-interacting protein 1, Anti-Cyclin-dependent kinase inhibitor 1, Anti-Melanoma... |
| Anwendung: | DB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-EGF Receptor / EGFR (Tyr1069)
Artikelnummer: NSJ-F48475-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | WB, DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-c-Myc (Thr58)
Artikelnummer: NSJ-F48482-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. c-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC...
| Schlagworte: | Anti-phospho-MYC, Anti-phospho-Proto-oncogene c-Myc, Anti-phospho-Transcription factor p64, Anti-phospho-Myc... |
| Anwendung: | DB, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-MDM2 (pT218)
Artikelnummer: NSJ-F48546-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MDM2 is a target of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of MDM2 can result in excessive...
| Schlagworte: | Anti-MDM2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3 ubiquitin-protein... |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-EGF Receptor / EGFR (Ser768)
Artikelnummer: NSJ-F48553-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix,...
| Schlagworte: | Anti-phospho-EGFR, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,... |
| Anwendung: | DB, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-LC3B / MAP1LC3B (pT12)
Artikelnummer: NSJ-F48560-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a...
| Schlagworte: | Anti-MAP1LC3B, Anti-Autophagy-related protein LC3 B, Anti-MAP1 light chain 3-like protein 2, Anti-Autophagy-related... |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €