Produkte von LKT Laboratories
LKT Laboratories, Inc. in St. Paul, Minnesota, ist ein Forschungs- und Entwicklungsunternehmen, das sich auf die Synthese, Aufreinigung und Isolierung von niedermolekularen Verbindungen konzentriert. Das 1989 gegründete Unternehmen produziert und vermarktet einzigartige (bio-)chemische Substanzen für verschiedenste naturwissenschaftliche Gebiete, insbesondere für die Krebs- und Neurowissenschaft. Bei der Herstellung dieser Wirkstoffe entstehen Substanzen, die auch für die Life-Science-Forschung als Bioreagenzien extrem nützlich sind und von LKT im analytischen Maßstab angeboten werden. Zu den Produkten zählen u.a. Proteinkinase-Inhibitoren sowie Ionenkanal-Modulatoren, die in diversen wissenschaftlichen Anwendungen zum Einsatz kommen.
Mehr Informationen unter: www.lktlabs.com
Für die Filterung wurden keine Ergebnisse gefunden!
Metyrapone
Artikelnummer: LKT-M184790.1
Metyrapone, an adrenal steroid synthesis Inhibitor that inhibits the steroid 11-beta-monooxygenase enzyme. SMILES: CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
| Schlagworte: | Metopirone, Methopyrapone, Metopiron, Methapyrapone, Methopirapone, Methopyrinine, Methopyrone, Metopyrone,... |
| Anwendung: | Steroidogenesis inhibitor |
| CAS | 54-36-4 |
| MW: | 226.27 D |
ab 73,00 €
Micafungin Sodium
Artikelnummer: LKT-M324081.100
Micafungin, an echinocandin, exhibits fungicidal and fungistatic activities through the inhibition of 1,3-beta-D-glucan synthesis. It was also found to have antiviral effects against various viruses including the coronavirus SARS-CoV-2 and its variants. SMILES:...
| Schlagworte: | Funguard, Mycamine, FK 463,Micafungin Na, FK463 Sodium, Micafungin sodium salt, FK-463 |
| Anwendung: | Echinocandin antifungal |
| CAS | 208538-73-2 |
| MW: | 1292.3 D |
ab 146,00 €
MK-3697
Artikelnummer: LKT-M403007.1
MK-3697 is a selective orexin 2 receptor antagonist. SMILES: CC1=CC(=CN=C1)C2=NC=C(C(=C2)C(=O)NCC3=NC(=C(C=C3)OC)OC)C4=NC=CS4
| Schlagworte: | MK3697, M8238285OA, N-((5,6-dimethoxy-2-pyridinyl)methyl)-5'-methyl-5-(2-thiazolyl)-(2,3'-Bipyridine)-4-carboxamide,... |
| Anwendung: | Orexin 2 receptor antagonist |
| CAS | 1224846-01-8 |
| MW: | 447.5 D |
ab 76,00 €
MSA-2
Artikelnummer: LKT-M721002.100
MSA-2 is an agonist of stimulator of interferon genes (STING). SMILES: COC1=C(C=C2C(=C1)C=C(S2)C(=O)CCC(=O)O)OC
| Schlagworte: | MSA2, 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid |
| Anwendung: | STING agonist |
| CAS | 129425-81-6 |
| MW: | 294.32 D |
ab 146,00 €
PF-07104091
Artikelnummer: LKT-P200091.1
PF-07104091 is a selective CDK2 inhibitor. SMILES: CC(C)NC(=O)OC1CCC(C1)C2=CC(=NN2)NC(=O)C3=CC(=NN3C)COC
| Schlagworte: | PF-07104091, PF 07104091, PF07104091, PF-7104091, PF 7104091, PF7104091,... |
| Anwendung: | CDK2 inhibitor |
| CAS | 2460249-19-6 |
| MW: | 404.47 D |
ab 229,00 €
PF-06873600
Artikelnummer: LKT-P200600.1
PF-06873600 is a selective inhibitor of CDK2/4/6 in multiple in vivo tumor models. SMILES: CC1(CCCC1N2C3=NC(=NC=C3C=C(C2=O)C(F)F)NC4CCN(CC4)S(=O)(=O)C)O
| Schlagworte: | PF06873600, Ebvaciclib,... |
| Anwendung: | CDK2/4/6 inhibitor |
| CAS | 2185857-97-8 |
| MW: | 471.52 D |
ab 222,00 €
PF-04745637
Artikelnummer: LKT-P200637.1
PF-04745637 is a selective antagonist for TRPA1 receptor. SMILES: C1CCC(C1)(C2=CC=C(C=C2)Cl)C(=O)NCC(CC3=CC=CC=C3)N4CCC(CC4)(C(F)(F)F)O
| Schlagworte: | 1-(4-chlorophenyl)-N-[2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]-3-phenylpropyl]cyclopentane-1-carboxamide |
| Anwendung: | TRPA1 antagonist |
| CAS | 1917294-46-2 |
| MW: | 509.01 D |
ab 100,00 €
RP-6306
Artikelnummer: LKT-P600006.1
RP-6306 is a protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1) inhibitor. SMILES: CC1=C(C(=C(C=C1)O)C)N2C(=C(C3=C2N=C(C(=C3)C)C)C(=O)N)N
| Schlagworte: | 2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethylpyrrolo[2,3-b]pyridine-3-carboxamide |
| Anwendung: | PKMYT1 inhibitor |
| CAS | 2719793-90-3 |
| MW: | 324.38 D |
ab 229,00 €
PRI-724
Artikelnummer: LKT-P691320.1
PRI-724 is an inhibitor of beta-catenin/CBP signaling and a potent antifibrotic agent. SMILES: CC1C2N(C(C(=O)N1CC3=CC=CC4=C3N=CC=C4)CC5=CC=C(C=C5)OP(=O)(O)O)C(=O)CN(N2C(=O)NCC6=CC=CC=C6)C
| Schlagworte: | PRI724, Foscenvivint,... |
| Anwendung: | Wnt/beta-catenin/CBP inhibitor |
| CAS | 1422253-38-0 |
| MW: | 658.65 D |
ab 222,00 €
Rifapentine
Artikelnummer: LKT-R327201.10
Rifapentine is an antibiotic shown to reduce infection and prevent reactivation of tuberculosis in infected macaques. A mouse model showed improved survival rate, alleviated clinical signs, reduced viral load, and reduced injury in target organs when treated with rifapentine. SMILES:...
| Schlagworte: | Rifapentin, Cyclopentylrafampicin,... |
| Anwendung: | Antibiotic |
| CAS | 61379-65-5 |
| MW: | 877.05 D |
ab 100,00 €
Simufilam
Artikelnummer: LKT-S336505.1
Simufilam was first introduced as having the potential to reduce biomarkers of Alzheimer's disease. The original data has since become suspect and could not be found. Fraud charges have been filed by the SEC. Simufilam may or may not have some useful bioactivities. The proper research, with proper data collection...
| Schlagworte: | PTI-125, PTI-910, C0105, 1,4,8-Triazaspiro(4.5)decan-2-one, 8-methyl-1-(phenylmethyl)-,... |
| Anwendung: | Unlikely to reverse Alzheimer's |
| CAS | 1224591-33-6 |
| MW: | 259.35 D |
ab 143,00 €
Simufilam Dihydrochloride
Artikelnummer: LKT-S336507.100
Simufilam was first introduced as having the potential to reduce biomarkers of Alzheimer's disease. The original data has since become suspect and could not be found. Fraud charges have been filed by the SEC. Simufilam may or may not have some useful bioactivities. The proper research, with proper data collection...
| Schlagworte: | PTI-125 dihydrochloride, PTI diHCl, JP8XRG9A58, 4-benzyl-8-methyl-1,4,8-triazaspiro[4.5]decan-3-one,dihydrochloride |
| Anwendung: | Unlikely to reverse Alzheimer's |
| CAS | 2480226-06-8 |
| MW: | 332.3 D |
ab 229,00 €