Produkte von LKT Laboratories
LKT Laboratories, Inc. in St. Paul, Minnesota, ist ein Forschungs- und Entwicklungsunternehmen, das sich auf die Synthese, Aufreinigung und Isolierung von niedermolekularen Verbindungen konzentriert. Das 1989 gegründete Unternehmen produziert und vermarktet einzigartige (bio-)chemische Substanzen für verschiedenste naturwissenschaftliche Gebiete, insbesondere für die Krebs- und Neurowissenschaft. Bei der Herstellung dieser Wirkstoffe entstehen Substanzen, die auch für die Life-Science-Forschung als Bioreagenzien extrem nützlich sind und von LKT im analytischen Maßstab angeboten werden. Zu den Produkten zählen u.a. Proteinkinase-Inhibitoren sowie Ionenkanal-Modulatoren, die in diversen wissenschaftlichen Anwendungen zum Einsatz kommen.
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H-151
Artikelnummer: LKT-H000051.100
SMILES: CCC1=CC=C(C=C1)NC(=O)NC2=CNC3=CC=CC=C32
| Schlagworte: | H151, N-(4-ethylphenyl)-N'-1H-indol-3-yl-urea, 1-(4-Ethylphenyl)-3-(1H-indol-3-yl) urea |
| Anwendung: | STING antagonist |
| CAS | 941987-60-6 |
| MW: | 279.34 D |
ab 100,00 €
(S,S)-ICG-001
Artikelnummer: LKT-I088240.1
(S,S)-ICG-001 is an inhibitor of Wnt/beta-catenin signaling. Treatment of nasopharyngeal carcinoma cells with ICG-001 led to reduced capability of the cells to adhere to extracellular matrix and capillary endothelial cells, and reduced tumor cell migration and invasion. In high-fat diet mice, treatment improved...
| Schlagworte: | beta-Catenin Inhibitor,... |
| Anwendung: | Wnt/beta-catenin inhibitor |
| CAS | 847591-62-2 |
| MW: | 548.63 D |
ab 139,00 €
Iloprost
Artikelnummer: LKT-I458579.1
Iloprost is a synthetic analogue of prostacyclin. This product includes a mixture of 4R and 4S diastereomers. SMILES: CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
| Schlagworte: | Cilaprost, Ventavis, Endoprost, Ilomedin, Iloprostum, UNII-JED5K35YGL, ZK-36374, JED5K35YGL,... |
| Anwendung: | Prostacyclin analog |
| CAS | 78919-13-8 |
| MW: | 360.5 D |
ab 313,00 €
(±)-Jasmonic Acid
Artikelnummer: LKT-J023736.100
Jasmonic acid is a naturally occurring hormone in plants that regulates plant growth, development, as well as serves as defense against stresses, insect attacks, and pathogen infections. It's anticancer activity on mammalian cells includes induction of apoptosis, inhibition of proliferation and tumor growth. SMILES:...
| Schlagworte: | Jasmonic Acid mixture of isomers, 2-[3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl]acetic acid |
| Anwendung: | Phytohormone |
| CAS | 221682-41-3 |
| MW: | 210.27 D |
ab 146,00 €
(-)-Jasmonic Acid
Artikelnummer: LKT-J023738.1
Jasmonic acid is a naturally occurring hormone in plants that regulates plant growth, development, as well as serves as defense against stresses, insect attacks, and pathogen infections. It's anticancer activity on mammalian cells includes induction of apoptosis, inhibition of proliferation and tumor growth. SMILES:...
| Schlagworte: | Jasmonic acid, Jasmonate, trans-Jasmonic Acid, 3-Oxo-2-(2-pentenyl)cyclopentaneacetic acid, (3R,7R)-Jasmonic acid,... |
| Anwendung: | Phytohormone |
| CAS | 6894-38-8 |
| MW: | 210.27 D |
ab 146,00 €
KB-0742
Artikelnummer: LKT-K040007.1
KB-0742 is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models. SMILES: CCC(CC)C1=NC2=CC=NN2C(=C1)NC3CCC(C3)N
| Schlagworte: | KB0742, NSC-834161, NSC834161, (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine |
| Anwendung: | CDK9 inhibitor. |
| CAS | 2170137-61-6 (base) |
| MW: | 287.41 D |
ab 283,00 €
KB-0742 dihydrochloride
Artikelnummer: LKT-K040009.1
KB-0742 dihydrochloride is a selective CDK9 inhibitor with potent anti-tumor activity in castration-resistant prostate cancer models.
| Schlagworte: | KB0742 dihydrochloride, NSC-834161 dihydrochloride, NSC834161 dihydrochloride,... |
| Anwendung: | CDK9 inhibitor. |
| CAS | 2416874-75-2 |
| MW: | 360.32 D |
ab 146,00 €
LHRH Acetate Salt
Artikelnummer: LKT-L302690.100
Luteinizing hormone-releasing hormone (LHRH or Gonadotropin-releasing hormone [GnRH]) is an endogenous peptide hormone that binds the GnRH receptor, stimulating secretion of reproductive hormones (such as luteinizing hormone [LH ] and follicle-stimulating hormone [FSH]) from the pituitary gland. Analogs of GnRH are...
| Schlagworte: | Gonadorelin, Gonadorelin acetate salt, Luliberin, GnRH, LH-RH, human, pEHWSYGLRPG-NH3 |
| Anwendung: | Endogenous peptide hormone, involved in secretion of reproductive hormones, GnRH agonist. |
| CAS | 33515-09-2 |
| MW: | 1182.31 D |
ab 360,00 €
LXH254
Artikelnummer: LKT-L930280.1
LXH254 is a type II RAF inhibitor. SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=NC=C2)C(F)(F)F)C3=CC(=NC(=C3)OCCO)N4CCOCC4
| Schlagworte: | Naporafenib,... |
| Anwendung: | pan-RAF inhibitor |
| CAS | 1800398-38-2 |
| MW: | 502.49 D |
ab 85,00 €
Metyrapone
Artikelnummer: LKT-M184790.1
Metyrapone, an adrenal steroid synthesis Inhibitor that inhibits the steroid 11-beta-monooxygenase enzyme. SMILES: CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
| Schlagworte: | Metopirone, Methopyrapone, Metopiron, Methapyrapone, Methopirapone, Methopyrinine, Methopyrone, Metopyrone,... |
| Anwendung: | Steroidogenesis inhibitor |
| CAS | 54-36-4 |
| MW: | 226.27 D |
ab 73,00 €
Micafungin Sodium
Artikelnummer: LKT-M324081.100
Micafungin, an echinocandin, exhibits fungicidal and fungistatic activities through the inhibition of 1,3-beta-D-glucan synthesis. It was also found to have antiviral effects against various viruses including the coronavirus SARS-CoV-2 and its variants. SMILES:...
| Schlagworte: | Funguard, Mycamine, FK 463,Micafungin Na, FK463 Sodium, Micafungin sodium salt, FK-463 |
| Anwendung: | Echinocandin antifungal |
| CAS | 208538-73-2 |
| MW: | 1292.3 D |
ab 146,00 €
MK-3697
Artikelnummer: LKT-M403007.1
MK-3697 is a selective orexin 2 receptor antagonist. SMILES: CC1=CC(=CN=C1)C2=NC=C(C(=C2)C(=O)NCC3=NC(=C(C=C3)OC)OC)C4=NC=CS4
| Schlagworte: | MK3697, M8238285OA, N-((5,6-dimethoxy-2-pyridinyl)methyl)-5'-methyl-5-(2-thiazolyl)-(2,3'-Bipyridine)-4-carboxamide,... |
| Anwendung: | Orexin 2 receptor antagonist |
| CAS | 1224846-01-8 |
| MW: | 447.5 D |
ab 76,00 €