Produkte von Innaxon

Innaxon

Innaxon ist ein Unternehmen mit Sitz in Tewkesbury, Vereinigtes Königreich, das sich auf angeborene Immunität, Toll-like Rezeptor (TLR)-Agonisten und niedermolekulare Inhibitoren konzentriert. Innaxon entwickelt und produziert definierte "Immunoceuticals" von höchster Aktivität und Reinheit für präklinische Forschungs- und Entwicklungsanwendungen für Impfstoffadjuvantien und Immuntherapie. Die einzigartigen biologischen und synthetischen TLR-Liganden von Innaxon sind gut charakterisierte und wirksame biologische Reaktionsmodifikatoren für unangemessene oder unverhältnismäßige Immunreaktionen.

Mehr Informationen unter: www.adipogen.com/innaxon

Zu den Katalogen von Innaxon

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Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution
Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution

Artikelnummer: IAX-100-001-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
Schlagworte: Lipid A derived from S. minnesota strain R595 (Re) TLRpure LPS (biosynthetic)
Anwendung: TLR4 activator
ab 153,00 €
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LPS from S. minnesota R595 (Re) TLRpure Sterile Solution
LPS from S. minnesota R595 (Re) TLRpure Sterile Solution

Artikelnummer: IAX-100-008-M001

Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R595 (Re), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 138,00 €
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LPS from E. coli J5 (Rc) TLRpure Sterile Solution
LPS from E. coli J5 (Rc) TLRpure Sterile Solution

Artikelnummer: IAX-100-014-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from E. coli strain J5 (Rc), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 172,00 €
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LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution
LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution

Artikelnummer: IAX-100-015-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R345 (Rb), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 172,00 €
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LPS from S. minnesota R60 (Ra) TLRpure Sterile Solution
LPS from S. minnesota R60 (Ra) TLRpure Sterile Solution

Artikelnummer: IAX-100-016-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R60 (Ra), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 194,00 €
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ODN 1585 (Type A) Endotoxin-free (sterile)
ODN 1585 (Type A) Endotoxin-free (sterile)

Artikelnummer: IAX-200-003-C100

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2218 (Cat. No.: IAX-200-203). Unmethylated CG dinucleotides within particular sequence contexts are...
Schlagworte: CpG ODN TLR9 Agonist: A Type (species: rodent)
Anwendung: TLR9 activator
MW: 6643 D
ab 191,00 €
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iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)

Artikelnummer: IAX-200-050-3001

3 x 1 mg. Potent sequence of an inhibitory ODN for in vivo use in rodents (50-150 µg per injection): prototype class I, may also affect TLR7 and TLR8 signaling. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
Schlagworte: Inhibitory ODN (iODN): Class I
Anwendung: TLR9 competitor
MW: 4887 D
ab 176,00 €
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Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re)...

Artikelnummer: IAX-100-002-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
Schlagworte: Monophosphoryl Lipid A [MPLA] derived from S. minnesota R595 (Re) TLRpure LPS (biosynthetic)
Anwendung: TLR4 activator
ab 208,00 €
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LPS from S. abortus equi (S-form) Biotin TLRpure Sterile Solution
LPS from S. abortus equi (S-form) Biotin TLRpure Sterile...

Artikelnummer: IAX-100-009B-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Biotinylated Lipopolysaccharide (LPS) from S. abortus equi, S-type (smooth/wild-type) LPS
Anwendung: TLR4 activator
ab 180,00 €
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LPS from E. coli  EH100 (Ra) TLRpure Sterile Solution
LPS from E. coli EH100 (Ra) TLRpure Sterile Solution

Artikelnummer: IAX-100-010-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from E. coli strain EH100 (Ra), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 172,00 €
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LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution
LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution

Artikelnummer: IAX-100-017-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R5 (Rc), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 172,00 €
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LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution
LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution

Artikelnummer: IAX-100-021-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Schlagworte: Lipopolysaccharide (LPS) from S. minnesota strain R3 (Rd2), R-type (rough/mutant) LPS
Anwendung: TLR4 activator
ab 172,00 €
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