Produkte von Innaxon
Innaxon ist ein Unternehmen mit Sitz in Tewkesbury, Vereinigtes Königreich, das sich auf angeborene Immunität, Toll-like Rezeptor (TLR)-Agonisten und niedermolekulare Inhibitoren konzentriert. Innaxon entwickelt und produziert definierte "Immunoceuticals" von höchster Aktivität und Reinheit für präklinische Forschungs- und Entwicklungsanwendungen für Impfstoffadjuvantien und Immuntherapie. Die einzigartigen biologischen und synthetischen TLR-Liganden von Innaxon sind gut charakterisierte und wirksame biologische Reaktionsmodifikatoren für unangemessene oder unverhältnismäßige Immunreaktionen.
Mehr Informationen unter: www.adipogen.com/innaxon
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IAXO-101 (CD14/TLR4 Antagonist) (synthetic)
Artikelnummer: IAX-600-001-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Schlagworte: | Methyl 6-deoxy-6-N-dimethyl-N-cyclopentylammonium-2,3-di-O-tetradecyl-?-D-glucopyranoside iodide |
| Anwendung: | CD14/TLR4 Antagonist |
| CAS | 1202388-64-4 |
| MW: | 810.02 D |
358,00 €
ODN 2395 (Type C) Endotoxin-free (sterile)
Artikelnummer: IAX-200-007-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
| Schlagworte: | CpG ODN: C Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 7068 D |
ab 191,00 €
LPS from E. coli R515 (Re) TLRpure Sterile Solution
Artikelnummer: IAX-100-007-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from E. coli strain R515 (Re), R-type (rough/mutant) LPS |
| Anwendung: | TLR4 activator |
ab 172,00 €
LPS (Universal) from S. abortus equi (S-form) TLRpure...
Artikelnummer: IAX-100-009-M001
Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by...
| Schlagworte: | Lipopolysaccharide (LPS) from Salmonella abortus equi, S-type (smooth/wild-type) LPS |
| Anwendung: | TLR4 activator |
ab 154,00 €
ODN 1826 (Type B) Endotoxin-free (sterile)
Artikelnummer: IAX-200-002-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1982 (Cat. No.: IAX-200-201).
| Schlagworte: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Anwendung: | TLR9 activator |
| Spezies-Reaktivität: | mouse, rat |
| MW: | 6383 D |
ab 191,00 €
ODN 2006 (Type B) Endotoxin-free (sterile)
Artikelnummer: IAX-200-006-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
| Schlagworte: | CpG ODN TLR9 Agonist: B Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 7720 D |
ab 191,00 €
Lipid A from E. coli R515 (Re) TLRpure Sterile Solution
Artikelnummer: IAX-100-004-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Schlagworte: | Lipid A derived from E. coli R515 (Re) LPS (biosynthetic) |
| Anwendung: | TLR4 activator |
ab 153,00 €
LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution
Artikelnummer: IAX-100-006-M001
Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by...
| Schlagworte: | Lipopolysaccharide (LPS) from E. coli O8:K27, S-type (smooth/wild-type) LPS |
| Anwendung: | TLR4 activator |
ab 124,00 €
LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution
Artikelnummer: IAX-100-018-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from S. minnesota strain R7 (Rd1), R-type (rough/mutant) LPS |
| Anwendung: | TLR4 activator |
ab 172,00 €
LPS from S. enteritidis (S-form) TLRpure Sterile Solution
Artikelnummer: IAX-100-019-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from Salmonella enteritidis, S-type (smooth/wild-type) LPS |
| Anwendung: | TLR4 activator |
ab 202,00 €
LPS from S. minnesota (S-form) TLRpure Sterile Solution
Artikelnummer: IAX-100-020-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Schlagworte: | Lipopolysaccharide (LPS) from Salmonella minnesota, S-type (smooth/wild-type) LPS |
| Anwendung: | TLR4 activator |
ab 172,00 €
ODN 2216 (Type A) Endotoxin-free (sterile)
Artikelnummer: IAX-200-005-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
| Schlagworte: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 6644 D |
ab 191,00 €