Produkte von GenScript

GenScript Biotech Corporation ist ein weltweit führender Anbieter von Forschungsprodukten zur Unterstützung von Innovationen in den Biowissenschaften. Das umfangreiche Portfolio umfasst kundenspezifische Gene, Peptide, Proteine, Antikörper und Oligonukleotide sowie eine breite Palette an CRISPR-Tools, Klonierungsvektoren, Expressionssystemen und Zellkulturreagenzien. Mit hohen Qualitätsstandards und zuverlässiger Lieferung ermöglicht GenScript Forschern weltweit, ihre Entdeckungen in den Bereichen Molekularbiologie, Immunologie und Arzneimittelentwicklung zu beschleunigen.

Mehr Informationen unter: www.genscript.com

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HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer[Biotin], His...

Artikelnummer: GSC-Z06507-100

Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.

Schlagworte:	B2M, Beta-2-microglobulin
Ursprungsart:	human
MW:	50.2 kD

ab 685,00 €

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HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer[Biotin],...

Artikelnummer: GSC-Z06508-100

Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.

Schlagworte:	B2M, Beta-2-microglobulin
Ursprungsart:	human
MW:	50.2 kD

ab 685,00 €

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HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer[Biotin],...

Artikelnummer: GSC-Z06509-100

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and...

Schlagworte:	B2M, Beta-2-microglobulin
Ursprungsart:	human
MW:	50.3 kD

ab 685,00 €

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HLA-G&B2M&Peptide (RIIPRHLQL) Monomer[Biotin], His & Avi,...

Artikelnummer: GSC-Z06522-100

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or...

Schlagworte:	B2M, Beta-2-microglobulin
Ursprungsart:	rhesus macaque
MW:	50.5 kD

ab 685,00 €

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Chimeric HLA-A*02:01 (m?3) &B2M&LMP2 (CLGGLLTMV) Monomer,...

Artikelnummer: GSC-Z06523-100

The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer...

Schlagworte:	H2-L, H-2 class I histocompatibility antigen, L-D alpha chain
MW:	50.3 kD

ab 457,00 €

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Chimeric HLA-A*02:01 (m?3) &B2M&LMP2 (CLGGLLTMV)...

Artikelnummer: GSC-Z06524-100

Schlagworte:	H2-L, H-2 class I histocompatibility antigen, L-D alpha chain
MW:	258 kD

ab 1.505,00 €

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Chimeric HLA-A*02:01 (m?3) &B2M&WT-1 (RMFPNAPYL)...

Artikelnummer: GSC-Z06526-100

The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and...

Schlagworte:	H2-L, H-2 class I histocompatibility antigen, L-D alpha chain
MW:	258 kD

ab 1.505,00 €

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HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer, His & Avi,...

Artikelnummer: GSC-Z06585-100

p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates...

Schlagworte:	B2M, Beta-2-microglobulin
Ursprungsart:	human
MW:	50.5 kD

ab 457,00 €

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HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer, His & Avi,...

Artikelnummer: GSC-Z06595-100

Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers, consequently, it has received significant attention as a...

Schlagworte:	B2M, Beta-2-microglobulin
Ursprungsart:	human
MW:	258 kD

ab 1.505,00 €

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HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer, His & Avi, Human

Artikelnummer: GSC-Z06600-100

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting...