Produkte von GenScript
GenScript Biotech Corporation ist ein weltweit führender Anbieter von Forschungsprodukten zur Unterstützung von Innovationen in den Biowissenschaften. Das umfangreiche Portfolio umfasst kundenspezifische Gene, Peptide, Proteine, Antikörper und Oligonukleotide sowie eine breite Palette an CRISPR-Tools, Klonierungsvektoren, Expressionssystemen und Zellkulturreagenzien. Mit hohen Qualitätsstandards und zuverlässiger Lieferung ermöglicht GenScript Forschern weltweit, ihre Entdeckungen in den Bereichen Molekularbiologie, Immunologie und Arzneimittelentwicklung zu beschleunigen.
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NEU
tPA hFc Chimera, Mouse
Artikelnummer: GSC-Z06387-100
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.
| Schlagworte: | Plat, Tissue-type plasminogen activator |
| Ursprungsart: | mouse |
| MW: | 85 kD |
ab 497,00 €
NEU
tPA, His, Mouse
Artikelnummer: GSC-Z06388-100
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.
| Schlagworte: | Plat, Tissue-type plasminogen activator |
| Ursprungsart: | mouse |
| MW: | 60.57 kD |
ab 497,00 €
NEU
TPBG/5T4, His, Mouse
Artikelnummer: GSC-Z06389-100
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
| Schlagworte: | Tpbg, Trophoblast glycoprotein, Wnt-activated inhibitory factor 1, 5T4 oncofetal trophoblast glycoprotein |
| Ursprungsart: | mouse |
| MW: | 36.86 kD |
ab 524,00 €
NEU
TRAIL R2/DR5/TNFRSF10B, His, Mouse
Artikelnummer: GSC-Z06390-100
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling...
| Schlagworte: | MK, Tnfrsf10b, Death receptor 5, Tumor necrosis factor receptor superfamily member 10B |
| Ursprungsart: | mouse |
| MW: | 15.3 kD |
ab 336,00 €
NEU
TYRO3, His, Mouse
Artikelnummer: GSC-Z06396-100
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew macrophage polarization towards a pro-tumor M2-like phenotype.In macrophages, the TAM receptors also...
| Schlagworte: | Tyro3, TK19-2, Etk2/tyro3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF, Tyrosine-protein kinase DTK,... |
| Ursprungsart: | mouse |
| MW: | 43 kD |
ab 457,00 €
NEU
uPAR/PLAUR Domain 3, His & Avi, Mouse
Artikelnummer: GSC-Z06398-100
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
| Schlagworte: | Plaur, Urokinase plasminogen activator surface receptor |
| Ursprungsart: | mouse |
| MW: | 11.83 kD |
ab 524,00 €
NEU
uPAR/PLAUR, His & Avi, Mouse
Artikelnummer: GSC-Z06399-100
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
| Schlagworte: | Plaur, Urokinase plasminogen activator surface receptor |
| Ursprungsart: | mouse |
| MW: | 32.92 kD |
ab 376,00 €
NEU
VCAM-1/CD106, His, Mouse
Artikelnummer: GSC-Z06400-100
Tumor necrosis factor alpha (TNFalpha) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFalpha induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was...
| Schlagworte: | Vcam1, Vascular cell adhesion protein 1 |
| Ursprungsart: | mouse |
| MW: | 75.48 kD |
ab 524,00 €
NEU
VNN1, His, Mouse
Artikelnummer: GSC-Z06402-100
Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a...
| Schlagworte: | Vnn1, Pantetheinase, Pantetheine hydrolase, Vascular non-inflammatory molecule 1 |
| Ursprungsart: | mouse |
| MW: | 53.14 kD |
ab 457,00 €
NEU
VSTM5 hFc Chimera, Mouse
Artikelnummer: GSC-Z06403-100
V-set and transmembrane domain-containing protein 5 (Vstm5), a cell-adhesion-like molecule belonging to the Ig superfamily, was found in mouse brain. Knock-down of Vstm5 in cultured hippocampal neurons markedly reduced the complexity of dendritic structures, as well as the number of dendritic filopodia. Vstm5 also...
| Schlagworte: | Vstm5, V-set and transmembrane domain-containing protein 5 |
| Ursprungsart: | mouse |
| MW: | 40.1 kD |
ab 457,00 €
NEU
WISP1, His, Mouse
Artikelnummer: GSC-Z06404-100
The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs...
| Schlagworte: | Ccn4, ELM-1, CCN family member 4, WNT1-inducible-signaling pathway protein 1 |
| Ursprungsart: | mouse |
| MW: | 39.4 kD |
ab 497,00 €
NEU
XPNPEP2, His, Mouse
Artikelnummer: GSC-Z06405-100
Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical significance of Aminopeptidase P2 in human cancers remains unknown.
| Schlagworte: | Xpnpep2, Xaa-Pro aminopeptidase 2, X-prolyl aminopeptidase 2, Membrane-bound aminopeptidase P |
| Ursprungsart: | mouse |
| MW: | 72.24 kD |
ab 578,00 €