Produkte von GenScript
GenScript Biotech Corporation ist ein weltweit führender Anbieter von Forschungsprodukten zur Unterstützung von Innovationen in den Biowissenschaften. Das umfangreiche Portfolio umfasst kundenspezifische Gene, Peptide, Proteine, Antikörper und Oligonukleotide sowie eine breite Palette an CRISPR-Tools, Klonierungsvektoren, Expressionssystemen und Zellkulturreagenzien. Mit hohen Qualitätsstandards und zuverlässiger Lieferung ermöglicht GenScript Forschern weltweit, ihre Entdeckungen in den Bereichen Molekularbiologie, Immunologie und Arzneimittelentwicklung zu beschleunigen.
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TGM3/Transglutaminase 3, His, Human
Artikelnummer: GSC-Z05876-100
TGM3, encoded by the TGM3 gene, is widely expressed in the small intestine, brain, skin and mucosa. In the skin and mucosa, TGM3 is predominantly expressed in the suprabasal layers of the stratified squamous epithelium. It has been demonstrated that TGM3 is essential for epidermal terminal differentiation and...
| Schlagworte: | TGM3, Transglutaminase E, Transglutaminase-3, Protein-glutamine gamma-glutamyltransferase E |
| Ursprungsart: | human |
| MW: | 78.23 kD |
ab 524,00 €
TIE1, His, Human
Artikelnummer: GSC-Z05879-100
TIE1 is a cell surface protein expressed in endothelial cells. Involved in angiogenesis and lymphangiogenesis, including morphogenesis of lymphatic valves, TIE1 is important for lymphatic system functional integrity.
| Schlagworte: | TIE1, Tyrosine-protein kinase receptor Tie-1 |
| Ursprungsart: | human |
| MW: | 80.93 kD |
ab 524,00 €
TNFR2/CD120b/TNFRSF1B mFc Chimera, Human
Artikelnummer: GSC-Z05896-100
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for...
| Schlagworte: | p75, TNFRSF1B, p80 TNF-alpha receptor, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, Tumor... |
| Ursprungsart: | human |
| MW: | 51.5 kD |
ab 403,00 €
TNFRSF11A/Rank hFc Chimera, Human
Artikelnummer: GSC-Z05897-100
TNFRSF11A, also known as receptor activator of NF-kappaB (RANK), activates several signaling pathways, such as NF-kappaB, JNK, ERK, p38alpha, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the...
| Schlagworte: | TNFRSF11A, Receptor activator of NF-KB, Osteoclast differentiation factor receptor, Tumor necrosis factor receptor... |
| Ursprungsart: | human |
| MW: | 46.85 kD |
ab 524,00 €
TNFRSF11B, His, Human
Artikelnummer: GSC-Z05898-100
Osteoprotegerin (OPG) is a key regulator in bone metabolism, that also has effect in vascular system. Studies suggest that osteoprotegerin is a critical arterial calcification inhibitor, and is released by endothelial cells as a protective mechanism for their survival in certain pathological conditions, such as...
| Schlagworte: | TNFRSF11B, Osteoprotegerin, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B |
| Ursprungsart: | human |
| MW: | 44.71 kD |
ab 497,00 €
TNFRSF12A/TWEAKR hFc Chimera, Human
Artikelnummer: GSC-Z05899-100
Thyroid cancer (TC) is the most well-known endocrine neoplasia as well as a common malignant tumor in the head and neck.TNFRSF12A expression may be a potential useful prognostic molecular biomarker of bad survival in thyroid cancer, in addition, PPAR signaling pathway, insulin signaling pathway, mTOR signaling...
| Schlagworte: | TNFRSF12A, Tweak-receptor, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible... |
| Ursprungsart: | human |
| MW: | 32.9 kD |
ab 349,00 €
Transthyretin/Prealbumin, His, Human
Artikelnummer: GSC-Z05920-100
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known, however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial...
| Schlagworte: | TTR, TBPA, ATTR, Prealbumin, Transthyretin |
| Ursprungsart: | human |
| MW: | 14.9 kD |
ab 403,00 €
TREM1, His, Human
Artikelnummer: GSC-Z05921-100
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.
| Schlagworte: | TREM1, Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1 |
| Ursprungsart: | human |
| MW: | 21.4 kD |
ab 524,00 €
TREM2 hFc Chimera, Human
Artikelnummer: GSC-Z05922-100
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail....
| Schlagworte: | TREM2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2 |
| Ursprungsart: | human |
| MW: | 44.2 kD |
ab 336,00 €
TREM2, His, Human
Artikelnummer: GSC-Z05923-100
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail....
| Schlagworte: | TREM2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2 |
| Ursprungsart: | human |
| MW: | 18.5 kD |
ab 524,00 €
TREML2/TLT-2, His, Human
Artikelnummer: GSC-Z05924-100
As an important family member of triggering receptor expressed on myeloid cells (TREM), TREM-like transcript 2 gene (TREML2) locates on human chromosome 6p21.1, a newly-identified hot zone for AD susceptibility, and encodes atransmembrane immune receptor. Emerging evidence implied a potential role of TREML2 in the...
| Schlagworte: | TREML2, Trem-like transcript 2 protein, Triggering receptor expressed on myeloid cells-like protein 2 |
| Ursprungsart: | human |
| MW: | 28.2 kD |
ab 551,00 €
TRIB3, GST, Human
Artikelnummer: GSC-Z05925-100
Tribbles homolog 3 (TRIB3) is a mammalian gene that is upregulated in response to several types of cell death-inducing cellular stress. The TRIB3 protein is a pseudokinase, a protein kinase-like scaffold with impaired catalytic activity.
| Schlagworte: | SINK, TRIB3, Tribbles homolog 3, p65-interacting inhibitor of NF-kappa-B, Neuronal cell death-inducible putative kinase |
| Ursprungsart: | human |
| MW: | 66.14 kD |
ab 497,00 €