Produkte von GenScript
GenScript Biotech Corporation ist ein weltweit führender Anbieter von Forschungsprodukten zur Unterstützung von Innovationen in den Biowissenschaften. Das umfangreiche Portfolio umfasst kundenspezifische Gene, Peptide, Proteine, Antikörper und Oligonukleotide sowie eine breite Palette an CRISPR-Tools, Klonierungsvektoren, Expressionssystemen und Zellkulturreagenzien. Mit hohen Qualitätsstandards und zuverlässiger Lieferung ermöglicht GenScript Forschern weltweit, ihre Entdeckungen in den Bereichen Molekularbiologie, Immunologie und Arzneimittelentwicklung zu beschleunigen.
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PD-L1/B7-H1, His, Human
Artikelnummer: GSC-Z05741-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Schlagworte: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Ursprungsart: | human |
| MW: | 24.93 kD |
ab 457,00 €
PD-L1/B7-H1 hFc Chimera, Human
Artikelnummer: GSC-Z05742-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Schlagworte: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Ursprungsart: | human |
| MW: | 52 kD |
ab 403,00 €
PD-L1/B7-H1 mFc Chimera, Human
Artikelnummer: GSC-Z05743-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Schlagworte: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Ursprungsart: | human |
| MW: | 50.9 kD |
ab 484,00 €
Periostin/OSF-2, His, Human
Artikelnummer: GSC-Z05748-100
Periostin is a matricellular protein that is expressed in several tissues during embryonic development, however, its expression in adults is mostly restricted to collagen-rich connective tissues. Periostin is expressed only briefly during kidney development, but it is not normally detected in the adult kidney....
| Schlagworte: | POSTN, Periostin, Osteoblast-specific factor 2 |
| Ursprungsart: | human |
| MW: | 92.1 kD |
ab 551,00 €
PGF hFc Chimera, Human
Artikelnummer: GSC-Z05749-100
Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV possibly via modulating their own expression in mononuclear phagocytes. PGF-related, optimized...
| Schlagworte: | PGF, Placenta growth factor |
| Ursprungsart: | human |
| MW: | 48.6 kD |
ab 349,00 €
PLA2G7, His, Human
Artikelnummer: GSC-Z05757-100
Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the...
| Schlagworte: | PLA2G7, PAF 2-acylhydrolase, Group-VIIA phospholipase A2, LDL-associated phospholipase A2, Platelet-activating factor... |
| Ursprungsart: | human |
| MW: | 48.9 kD |
ab 497,00 €
PLAU/uPA (active form), His, Human
Artikelnummer: GSC-Z05758-100
Plasminogen activator, urokinase (uPA) is a secreted serine protease, cleaving the sequence Cys-Pro-Gly-Arg560-Val561-Val-Gly-Gly-Cys in plasminogen to form plasmin. Dysregulation of PLAU is often accompanied by various cancers and PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for...
| Schlagworte: | PLAU, Urokinase-type plasminogen activator |
| Ursprungsart: | human |
| MW: | 18/29/15 kD |
ab 497,00 €
PRL-2/PTP4A2, His, Human
Artikelnummer: GSC-Z05766-100
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators.PRL-2 is a member of PTP family and has an important function in controlling cell growth.
| Schlagworte: | OV-1, PTP4A2, HU-PP-1, PTP(CAAXII), Protein-tyrosine phosphatase 4a2, Protein tyrosine phosphatase type IVA 2,... |
| Ursprungsart: | human |
| MW: | 19.89 kD |
ab 457,00 €
PSMP hFc Chimera, Human
Artikelnummer: GSC-Z05776-100
PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern...
| Schlagworte: | MSMP, PC3-secreted microprotein, Prostate-associated microseminoprotein |
| Ursprungsart: | human |
| MW: | 37.9 kD |
ab 457,00 €
RNF43 hFc Chimera, Human
Artikelnummer: GSC-Z05791-100
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/beta-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the...
| Schlagworte: | RNF43, RING finger protein 43, E3 ubiquitin-protein ligase RNF43, RING-type E3 ubiquitin transferase RNF43 |
| Ursprungsart: | human |
| MW: | 45.8 kD |
ab 457,00 €
ROBO4, His, Human
Artikelnummer: GSC-Z05792-100
Roundabout4 (Robo4) is a transmembrane receptor that belongs to the Roundabout (Robo) family of axon guidance molecules. Robo4 is an endothelial-specific receptor that participates in endothelial cell migration, proliferation, and angiogenesis and the maintenance of vasculature homeostasis. Robo4 is a promising and...
| Schlagworte: | ROBO4, Magic roundabout, Roundabout homolog 4 |
| Ursprungsart: | human |
| MW: | 47.8 kD |
ab 457,00 €
ROR2/NTRKR2 hFc Chimera, Human
Artikelnummer: GSC-Z05793-100
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa)...
| Schlagworte: | ROR2, Neurotrophic tyrosine kinase, receptor-related 2, Tyrosine-protein kinase transmembrane receptor ROR2 |
| Ursprungsart: | human |
| MW: | 68 kD |
ab 524,00 €