Produkte von GenScript
GenScript Biotech Corporation ist ein weltweit führender Anbieter von Forschungsprodukten zur Unterstützung von Innovationen in den Biowissenschaften. Das umfangreiche Portfolio umfasst kundenspezifische Gene, Peptide, Proteine, Antikörper und Oligonukleotide sowie eine breite Palette an CRISPR-Tools, Klonierungsvektoren, Expressionssystemen und Zellkulturreagenzien. Mit hohen Qualitätsstandards und zuverlässiger Lieferung ermöglicht GenScript Forschern weltweit, ihre Entdeckungen in den Bereichen Molekularbiologie, Immunologie und Arzneimittelentwicklung zu beschleunigen.
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Notch 3 hFc Chimera, Human
Artikelnummer: GSC-Z05704-100
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring...
| Schlagworte: | NOTCH3, Neurogenic locus notch homolog protein 3 |
| Ursprungsart: | human |
| MW: | 71.53 kD |
ab 524,00 €
OSCAR hFc Chimera, Human
Artikelnummer: GSC-Z05716-100
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not...
| Schlagworte: | OSCAR, Polymeric immunoglobulin receptor 3, Osteoclast-associated immunoglobulin-like receptor |
| Ursprungsart: | human |
| MW: | 49.8 kD |
ab 497,00 €
OSMR beta, His, Human
Artikelnummer: GSC-Z05720-100
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases...
| Schlagworte: | OSMR, Interleukin-31 receptor subunit beta, Oncostatin-M-specific receptor subunit beta |
| Ursprungsart: | human |
| MW: | 82.2 kD |
ab 497,00 €
Osteomodulin, His, Human
Artikelnummer: GSC-Z05724-100
Osteomodulin (OMD) is a member of the small leucine-rich repeat proteoglycan family, which is involved in the organization of the extracellular matrix. OMD is located in bone tissue and is reportedly important for bone mineralization. Mechanistically, OMD could bind to BMP2 via its terminal leucine-rich repeats and...
| Schlagworte: | OMD, Osteomodulin, Osteoadherin, Keratan sulfate proteoglycan osteomodulin |
| Ursprungsart: | human |
| MW: | 48.25 kD |
ab 457,00 €
OX40 Ligand/TNFSF4 hFc Chimera, Human
Artikelnummer: GSC-Z05725-100
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
| Schlagworte: | TNFSF4, OX40 ligand, Glycoprotein Gp34, TAX transcriptionally-activated glycoprotein 1, Tumor necrosis factor ligand... |
| Ursprungsart: | human |
| MW: | 40.95 kD |
ab 457,00 €
PAH (D415N), His, Human
Artikelnummer: GSC-Z05730-100
Phenylalanine hydroxylase (PAH) is a member of aromatic amino acid hydroxylase (AAAHs) family, and catalyze phenylalanine (Phe) into tyrosine (Tyr). PAH is also an allosteric enzyme that maintains phenylalanine (Phe) below neurotoxic levels, its failure results in phenylketonuria, an inborn error of amino acid...
| Schlagworte: | PAH, Phe-4-monooxygenase, Phenylalanine-4-hydroxylase |
| Ursprungsart: | human |
| MW: | 52.82 kD |
ab 497,00 €
PAI-1, His, Human
Artikelnummer: GSC-Z05731-100
PAI-1 (plasminogen activator inhibitor-1) is a member of plasminogen cascade with an inhibitory role in plasmin activation. PAI-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resistant states.
| Schlagworte: | SERPINE1, Serpin E1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor |
| Ursprungsart: | human |
| MW: | 43.86 kD |
ab 403,00 €
PBK/TOPK, His, Human
Artikelnummer: GSC-Z05732-100
T-lymphokine-activated killer cell-originated protein kinase (TOPK, also known as PDZ-binding kinase or PBK) plays a crucial role in cell cycle regulation and mitotic progression. Abnormal overexpression or activation of TOPK has been observed in many cancers, including colorectal cancer, triple-negative breast...
| Schlagworte: | PBK, Nori-3, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK cell-originated protein... |
| Ursprungsart: | human |
| MW: | 37.61 kD |
ab 524,00 €
PCSK9, His, Human
Artikelnummer: GSC-Z05733-100
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injections, by the U.S. Food and Drug Administration in 2015 for lowering LDL-particle concentrations...
| Schlagworte: | PCSK9, Proprotein convertase 9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, Proprotein... |
| Ursprungsart: | human |
| MW: | 14-68 kD |
ab 524,00 €
PD-1/PDCD1 hFc Chimera, Human
Artikelnummer: GSC-Z05734-100
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Ursprungsart: | human |
| MW: | 42.6 kD |
ab 403,00 €
PD-1/PDCD1 mFc Chimera, Human
Artikelnummer: GSC-Z05735-100
Programmed Death-1 receptor (PD-1), also known as CD279, is type I transmembrane protein belonging to the CD28 family of immune regulatory receptors.PD1 is a inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory...
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Ursprungsart: | human |
| MW: | 41.6 kD |
ab 457,00 €
PDGF R beta/CD140b, His & Avi, Human
Artikelnummer: GSC-Z05738-100
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF...
| Schlagworte: | PDGFRB, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, Beta platelet-derived growth factor... |
| Ursprungsart: | human |
| MW: | 59 kD |
ab 376,00 €