Produkte von GenScript
GenScript Biotech Corporation ist ein weltweit führender Anbieter von Forschungsprodukten zur Unterstützung von Innovationen in den Biowissenschaften. Das umfangreiche Portfolio umfasst kundenspezifische Gene, Peptide, Proteine, Antikörper und Oligonukleotide sowie eine breite Palette an CRISPR-Tools, Klonierungsvektoren, Expressionssystemen und Zellkulturreagenzien. Mit hohen Qualitätsstandards und zuverlässiger Lieferung ermöglicht GenScript Forschern weltweit, ihre Entdeckungen in den Bereichen Molekularbiologie, Immunologie und Arzneimittelentwicklung zu beschleunigen.
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IL-18 R1/CD218a, His & Avi, Human
Artikelnummer: GSC-Z05452-100
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-gamma production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon...
| Schlagworte: | IL18R1, CDw218a, Interleukin-18 receptor 1, IL1 receptor-related protein, Interleukin-18 receptor alpha, CD218... |
| Ursprungsart: | human |
| MW: | 38.8 kD |
ab 228,00 €
IL-18BP hFc Chimera, Human
Artikelnummer: GSC-Z05453-100
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy...
| Schlagworte: | IL18BP, Tadekinig-alfa, Interleukin-18-binding protein |
| Ursprungsart: | human |
| MW: | 44.4 kD |
ab 228,00 €
IL-18BP, His, Human
Artikelnummer: GSC-Z05454-100
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy...
| Schlagworte: | IL18BP, Tadekinig-alfa, Interleukin-18-binding protein |
| Ursprungsart: | human |
| MW: | 18.7 kD |
ab 202,00 €
IL-1RL1/ST2 hFc Chimera, Human
Artikelnummer: GSC-Z05467-100
IL1RL1(also known as ST2) is a member of the IL1 receptor family and serves as the receptor for IL-33. The ST2 protein has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect....
| Schlagworte: | IL1RL1, Protein ST2, Interleukin-1 receptor-like 1 |
| Ursprungsart: | human |
| MW: | 61.75 kD |
ab 228,00 €
IL-1RL1/ST2, His, Human
Artikelnummer: GSC-Z05468-100
IL1RL1(also known as ST2) is a member of the IL1 receptor family and serves as the receptor for IL-33. The ST2 protein has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect....
| Schlagworte: | IL1RL1, Protein ST2, Interleukin-1 receptor-like 1 |
| Ursprungsart: | human |
| MW: | 36 kD |
ab 255,00 €
IL-2, Human
Artikelnummer: GSC-Z05469-100
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system,...
| Schlagworte: | IL2, Interleukin-2, T-cell growth factor |
| Ursprungsart: | human |
| MW: | 15.41 kD |
ab 202,00 €
IL-22, His, Human
Artikelnummer: GSC-Z05478-100
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
| Schlagworte: | IL22, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor |
| Ursprungsart: | human |
| MW: | 17.8 kD |
ab 497,00 €
IL-23 alpha&IL-12 beta, His, Human
Artikelnummer: GSC-Z05481-100
The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD). Targeting this pathway has opened new avenues for therapeutic intervention. The balance of proinflammatory cytokines interleukin...
| Schlagworte: | IL12A, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte... |
| Ursprungsart: | human |
| MW: | 19.77/34.7 kD |
ab 524,00 €
IL-23 alpha&IL-12 beta, His & Avi, Human&Mouse
Artikelnummer: GSC-Z05482-100
Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common beta subunit p40 and the specific cytokine alpha subunit p35 and p19, respectively. IL-12 signals via the IL-12Rbeta1·IL-12Rbeta2 receptor complex, and IL-23 uses also IL-12Rbeta1 but engages IL-23R as...
| Schlagworte: | IL12A, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte... |
| MW: | 21.7/35.8 kD |
ab 793,00 €
IL-23 P19/IL-23A hFc Chimera, Human
Artikelnummer: GSC-Z05483-100
IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by inducing the expansion of CD4(+) cells producing IL-17.
| Schlagworte: | IL23A, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Ursprungsart: | human |
| MW: | 45.43 kD |
ab 497,00 €
IL-31, His, Human
Artikelnummer: GSC-Z05496-100
Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the...
| Schlagworte: | IL31, Interleukin-31 |
| Ursprungsart: | human |
| MW: | 16.9 kD |
ab 524,00 €
IL-31 RA hFc Chimera, Human
Artikelnummer: GSC-Z05498-100
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is...
| Schlagworte: | GLM-R, IL31RA, ZcytoR17, Cytokine receptor-like 3, Gp130-like monocyte receptor, Interleukin-31 receptor subunit alpha |
| Ursprungsart: | human |
| MW: | 83.8 kD |
ab 524,00 €