Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Human TNFRSF11A Protein, hFc Tag
Artikelnummer: DIM-PME100853.10
Recombinant human TNFRSF11A protein with C-terminal human Fc tag. TNFRSF11A(Ile30-Pro212) hFc(Glu99-Ala330), Protein function: Receptor for TNFSF11/RANKL/TRANCE/OPGL, essential for RANKL- mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. [The UniProt...
| Schlagworte: | Tumor necrosis factor receptor superfamily member 11A, ODFR, Receptor activator of NF-KB, CD265, RANK |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 46.2 kD |
ab 105,00 €
Human APRIL Protein, hFc Tag
Artikelnummer: DIM-PME100854.10
Recombinant Human APRIL Protein with N-terminal human Fc tag. hFc(Glu99-Ala330) APRIL(Ala105-Leu250), Protein function: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. [The...
| Schlagworte: | TNFSF13, CD256, TALL2, ZTNF2, TALL-2, TNLG7B, TRDL-1, UNQ383/PRO715 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 42.5 kD |
ab 102,00 €
Human VSIG4 Protein, hFc Tag
Artikelnummer: DIM-PME100855.10
Recombinant Human VSIG4 with C-terminal human Fc tag. VSIG4(Arg20-Pro283) hFc(Glu99-Ala330), Protein function: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. [The UniProt Consortium]
| Schlagworte: | CRIg, Z39IG |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 55.3 kD |
ab 124,00 €
Human PROM1 Protein, hFc Tag
Artikelnummer: DIM-PME100857.10
Recombinant human PROM1 protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) PROM1 (Gly20-Gly108), Protein function: May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the...
| Schlagworte: | AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 36.6 kD |
ab 120,00 €
Human CD1A Protein, hFc Tag
Artikelnummer: DIM-PME100859.10
Recombinant human CD1A protein with C-terminal human Fc tag. CD1A(Asp19-Ser298) hFc(Glu99-Ala330), Protein function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. [The UniProt Consortium]
| Schlagworte: | R4, T6, CD1, FCB6, HTA1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 58.1 kD |
ab 146,00 €
Human ITGAV and ITGB1 Heterodimer Protein, His Tag and...
Artikelnummer: DIM-PME100861.10
Recombinant heterodimer protein containg both human ITGAV Protein with C-terminal 6×His tag and human ITGB1 protein with C-terminal human Fc tag. ITGAV(Phe31-Val992) 6×His tag - ITGB1(Gln21-Asp728) hFc(Glu99-Ala330), Protein function: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin,...
| Schlagworte: | Integrin alpha V beta 1, ITGAVandITGB1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 107.1/ kD |
ab 176,00 €
Human CLDN3 Protein, hFc Tag
Artikelnummer: DIM-PME100862.10
Recombinant human CLDN3 protein with C-terminal human Fc tag. CLDN3(Arg30-Arg80) hFc(Glu99-Ala330), Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Schlagworte: | C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 31.8 kD |
ab 176,00 €
Human COLEC10 Protein, hFc Tag
Artikelnummer: DIM-PME100863.10
Recombinant Human COLEC10 Protein with C-terminal human Fc tag. COLEC10(Leu28-Lys277) hFc(Glu99-Ala330), Protein function: Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine (PubMed:10224141). Acts as a chemoattractant, probably involved in the regulation...
| Schlagworte: | 3MC3, CL-10, CL-34, CLL1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 53.8 kD |
ab 176,00 €
Human FOLR2 Protein, hFc Tag
Artikelnummer: DIM-PME100868.10
Recombinant Human FOLR2 with C-terminal human Fc tag. FOLR2(Thr17-His228) hFc(Glu99-Ala330), Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at...
| Schlagworte: | BETA-HFR, FBP, FBP/PL-1, FOLR1, FR-BETA, FR-P3, FRbeta |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 50.7 kD |
ab 119,00 €
Human GDNF Protein, hFc Tag
Artikelnummer: DIM-PME100870.10
Recombinant Human GDNF with C-terminal human Fc tag. GDNF(Ser78-Ile211) hFc(Glu99-Ala330), Protein function: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. [The UniProt Consortium]
| Schlagworte: | ATF, ATF1, ATF2, HFB1-GDNF, HSCR3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 41.2 kD |
ab 120,00 €
Human GNRHR Protein, hFc Tag
Artikelnummer: DIM-PME100871.10
Recombinant Human GNRHR Protein with C-terminal human Fc tag. GNRHR(Met1-Arg38) hFc(Glu99-Ala330), Protein function: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone...
| Schlagworte: | GNRHR1, GRHR, HH7, LHRHR, LRHR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 30.2 kD |
ab 151,00 €
Human IL13 Protein, hFc Tag
Artikelnummer: DIM-PME100872.10
Recombinant human IL13 protein with C-terminal human Fc tag. IL13(Thr21-Leu132) hFc(Glu99-Ala330), Protein function: Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in...
| Schlagworte: | IL-13, NC30 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 38.1 kD |
ab 183,00 €